3 edition of Prostaglandin E₂ prevents ovariectomy-induced cancellous bone loss in rats found in the catalog.
Prostaglandin E₂ prevents ovariectomy-induced cancellous bone loss in rats
by National Aeronautics and Space Administration, National Technical Information Service, distributor in [Washington, DC, Springfield, Va
Written in English
|Other titles||Prostaglandin E₂ prevents ovariectomy induced cancellous bone loss in rats.|
|Statement||Hua Zhu Ke, Mei Li, and Webster S.S. Jee.|
|Series||[NASA contractor report] -- NASA-CR-202468., NASA contractor report -- NASA CR-202468.|
|Contributions||Li, Mei., Jee, Webster S. S., United States. National Aeronautics and Space Administration.|
|The Physical Object|
Atomic minerals are the smallest components of bone and the content of Ca, being the most abundant mineral in bone, correlates strongly with the risk of osteoporosis. Postmenopausal women have a far greater risk of suffering from OP due to low Ca concentrations in their bones and this is associated with low bone mass and higher bone fracture rates. However, bone strength is determined not only. JPB2 JPA JPA JPB2 JP B2 JP B2 JP B2 JP A JP A JP A JP A JP A JP A JP B2 JP B2 JP B2 Authority JP Japan Prior art keywords mg kg cancer moha cells Prior art date Legal status (The legal status is an assumption .
IN many species luteolysis is dependent upon the presence of the uterus and an intact utero-ovarian vasculature. The occurrence of prostaglandin F2α (PGF2α) in uterine tissue, its specific. Subcutaneous administration of leptin attenuates bone loss in ovariectomized (ovx) rats by reducing bone resorption. However, in addition to its direct beneficial effects, leptin has been reported to have indirect (central nervous system-mediated) antiosteogenic effects on bone, which may limit the efficacy of elevated serum leptin to prevent estrogen deficiency-associated bone loss.
Start studying Prostaglandins. Learn vocabulary, terms, and more with flashcards, games, and other study tools. 1. Olley PM, Coceani F. Use of prostaglandins in cardiopulmonary diseases of the newborn. Semin Perinatol ; 2. Heymann MA. Pharmacologic use of prostaglandin E1 in infants with congenital heart disease. Am Heart J ; 3. Freed MD, Heymann MA, Lewis AB, Roehl SL, Kensey RC. Prostaglandin E1 in infants with ductus.
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Zhanjiang Medical College, Guangdong Province, People's Republic of China (Received 3 March ) (Accepted 21 May ) Summary The object of this study was to determine whether prostaglandin Ez (PGEz) can prevent ovariectomy- induced cancellous bone loss, Thirty-five 3-month-old female Sprague-Dawley rats were divided into two by: The object of this study was to determine whether prostaglandin E., (PGE2) can prevent ovariectomy-induced cancellous bone loss.
Thirty-five 3-month-old female Sprague-Dawley rats were divided into two groups. The rats in the first group were ovariectomized (OVX) while the others received sham operation (sham-OVX). Get this from a library. Prostaglandin E₂ prevents ovariectomy-induced cancellous bone loss in rats.
[Hua Zhu Ke; Mei Li; Webster S S Jee; United States. National Aeronautics and Space Administration.]. Bone and Mineral. 19 () ' 45 BAM Prostaglandin E 2 prevents ovariectomy-induced cancellous bone loss in rats Hua Zhu Ke ab, Mei Li a and Webster S.S.
Jee a a Division of Radiobiology, University of Utah School of Medicine, Salt Lake City. Prostaglandin E2 prevents ovariectomy-induced cancellous bone loss in the rats. Bone Miner ; 43 Rockoff SD, Sweet E, Bluestein J.
The relative contribution of trabecular and cortical bone to the strength of human lumbar by: Prostaglandin E 2 (PGE 2) is a bone anabolic agent that has been shown to increase bone mass by significantly increasing bone formation over bone resorption.6 The skeletal anabolic effects of PGE 2 have been demonstrated in both young and adult intact male and female rats.6, 10, 11, 12, 18 When given to ovariectomized (ovx) or orchidectomized (orx) rats immediately following surgery, PGE 2.
Postmenopausal osteoporosis due to estrogen deficiency is associated with severe morbidity and mortality. Beneficial effects of conjugated linoleic acid (CLA) on bone mineral density (BMD) have been reported in mice, rats and humans, but the effect of long term CLA supplementation against ovariectomy-induced bone loss in mice and the mechanisms underlying this effect have not been studied by: 9.
To unveil the relationship between changes in BMD and bone marrow haematopoiesis in adult animals suffering from osteoporosis, we chose 3-month-old rats as experimental models.
Several previous studies showed that in rats, oestrogen levels decreased precipitously accompanied by bone mass loss following ovariectomy. The object of this study was to determine whether prostaglandin E2 (PGE2) can prevent ovariectomy-induced cancellous bone loss.
Thirty-five 3-month-old female Sprague-Dawley rats were divided into. Our findings indicate that ovariectomy-induced bone loss in the rat is accompanied by marked changes in the hematopoietic system, and that these changes are modulated by estrogen administration.
In spite of the negative finding with IL-1ra, the nature of the involvement of the hematopoietic system in the pathogenesis of bone loss due to ovarian hormone deficiency merits continued exploration. Ke HZ, Li M, Jee WSS (b) Prostaglandin2 prevents ovariectomy-induced cancellous bone loss in rat.
Bone Miner 9: 45–62 CrossRef Google Scholar Kimmel DB () The oophorectomized beagle as an experimental model for estrogen-depletion bone loss in adult human. The purpose of this study was to determine whether prostaglandin E 2 (PGE 2) can restore cancellous bone mass and architecture to osteopenic, continuously immobilized (IM), proximal tibial metaphysis (PTM) in female right hindlimb of three and one-half-month-old Sprague-Dawley female rats were immobilized by right hindlimb immobilization (RHLI) in which the right hindlimb was.
Prostaglandins have been reported to mediate the effects of ovariectomy on bone loss. We studied the effect of naproxen, an inhibitor of production of prostaglandins, on ovariectomy-induced bone loss. Mo A, Yao W, Li C, et al.
Bipedal stance exercise and prostaglandin E2 (PGE2) and its synergistic effect in increasing bone mass and in lowering the PGE2 dose required to prevent ovariectomized-induced cancellous bone loss in aged rats.
Prostaglandins (E 1, E 2, F 1α and F 2α) evoke increased vascular permeability in the skin of rat and man 7, which appears to be an indirect effect resulting from mast cell degranulation. The effect of acetylsalicylic acid (aspirin) on bone mass and bone prostaglandin E (PGE) in immobilization osteoporosis was studied in 12 growing dogs.
week), there was a prevention of ovariectomy-induced bone loss at the femur at 6 and 8 weeks; no sign ificant dif ferences w ith respect to zero dose were noted at other sites. Request PDF | On Oct 1,Rahul S.
Chaudhari and others published β-Cryptoxanthin rich Paprika extract prevents ovariectomy induced bone loss in Wistar rats | Find, read and cite all the. Abstract. Ovariectomy-induced osteopenia in the rat produces skeletal responses similar to that in a post-menopausal woman.
In the ovariectomized (ovx) rat, high bone turnover, and subsequent bone loss, like in the human post-menopausal condition, can be prevented by estrogen replacement. Akamine T, Jee WSS, Ke HZ, Lin BY () Prostaglandin E2 prevents bone loss and adds extra bone to immbolized distal femoral metaphysis in female rats.
Bone 11–22 CAS. Abstract. The ovary is concerned with the secretion of steroid hormones and with the release of a mature ovum (ovulation). Ovarian function is controlled by hormones secreted by the anterior pituitary gland, namely follicle-stimulating hormone (FSH), luteinizing hormone (LH), and, to a greater or lesser extent depending upon the species, prolactin.In this study, we aim to investigate the effects of methylprednisolone, a glucocorticoid, on ovariectomy-induced bone loss in rats with a metyrosine-reduced amount of endogenous adrenaline and compare them with alendronate.
Severity of bone loss in the examined femur bone tissues were evaluated with BMD measurements.Prostaglandins and its Analogues: An approach for Treatment of Anoestrus and to enhance Breeding Efficiency 90% of all dairy cows becomes infected with bacteria The molecular formula and molecular weight of .
Delayed uterine clearance which leads to retention cloprostenol sodium are C 22 H 28 ClNaO 6 and